Melanotan II (MT-II) is a synthetic analog of the peptide hormone alpha-melanocyte-stimulating hormone (α-MSH), designed to activate multiple melanocortin receptors, including MC1R, MC3R, MC4R, and MC5R. Originally developed for its potential in treating sexual dysfunction and promoting skin tanning, MT-II has gained recognition for its ability to enhance skin pigmentation, stimulate sexual arousal, and suppress appetite. Despite its growing interest, Melanotan II remains unapproved for medical use in most countries and is classified as an unregulated substance.
